Live imaging of meiosis in yeast

Description

Wolfgang Zachariae‘s lab from the Max Planck Institute for Biochemistry used temperature-sensitive alleles in yeast to study chromosome separation during meiosis. Shifting yeast from 25°C to 37°C while simultaneously doing live cell imaging? Ideal application for our instrument!

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References

“Mengoli, V., Jonak, K., Lyzak, O., Lamb, M., Lister, L., Lodge, C., Rojas, J., Zagoriy, I., Herbert, M., & Zachariae, W. (2021). Deprotection of centromeric cohesin at meiosis II requires APC/C activity but not kinetochore tension. The EMBO Journal, 40(7).”

V. Mengoli EMBO journal (2021)

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