Thermo-responsive phase separation of DNA-droplets

Description

The lab of Andreas Walther from University of Mainz used VAHEAT to observe the droplet formation process and structural transformations during a heating cycle (25 → 85 °C). Population of droplets appears after 20 s at 85 °C, and successively, the spherical droplets grow and eventually undergo coalescence.

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References

“Liu, W., Samanta, A., Deng, J., Akintayo, C. O., & Walther, A. (2022). Mechanistic Insights into the Phase Separation Behavior and Pathway‐Directed Information Exchange in all‐DNA Droplets. Angewandte Chemie International Edition, 61(45).”

Liu, W. Angewandte Chemie International Edition (2022)

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